GSK345931A

Names

[ CAS No. ]:
869499-38-7

[ Name ]:
GSK345931A

[Synonym ]:
unii-u73bv4mml7

Biological Activity

[Description]:

GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[Target]

EP1


[References]

[1]. Hall A, et al. Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett. 2009 Jan 15;19(2):497-501.  

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19ClNNaO3

[ Molecular Weight ]:
403.83

[ Exact Mass ]:
403.09500

[ PSA ]:
62.25000

[ LogP ]:
4.46730

Related Compounds