(E)-7-Fluoro-4-hydrazono-4,5-dihydropyrrolo[1,2-a]quinoxaline

Names

[ CAS No. ]:
895159-28-1

[ Name ]:
(E)-7-Fluoro-4-hydrazono-4,5-dihydropyrrolo[1,2-a]quinoxaline

Biological Activity

[Description]:

(E)-7-Fluoro-4-hydrazono-4,5-dihydropyrrolo[1,2-a]quinoxaline is an intermediate, which can be used in the synthesis of SC144. SC144 is a potent agent with broad-spectrum cytotoxic activities in a number of tumor cells. SC144 shows excellent potency against a panel of human cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Plasencia C, et al. Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity. Cancer Biol Ther. 2009 Mar;8(5):458-65.

Chemical & Physical Properties

[ Molecular Formula ]:
C11H9FN4

[ Molecular Weight ]:
216.21