55156-24-6

55156-24-6 structure
55156-24-6 structure

Name sodium,(Z,2S)-2-[[(Z,2S)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-6-diazonio-5-oxidohex-5-enoyl]amino]-6-diazonio-5-oxidohex-5-enoate
Synonyms Antibiotic 1719 sodium salt
Azotomycin sodium salt
Azotomycin sodium
1719 Sodium
Molecular Formula C17H22N7NaO8
Molecular Weight 475.38800
Exact Mass 475.14300
PSA 271.05000

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC6311000
CHEMICAL NAME :
L-Norleucine, 6-diazo-N-(6-diazo-N-L-gamma-glutamyl-5-oxo-L-norleuc yl)-5-oxo-, sodium salt
CAS REGISTRY NUMBER :
55156-24-6
LAST UPDATED :
199509
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C17-H23-N7-O8.xNa
MOLECULAR WEIGHT :
614.40
WISWESSER LINE NOTATION :
QVYZ2VMY2V1UNN&VMYVQ2V1UNN &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
388 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
262 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea Liver - other changes
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,3467,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
271 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4300 ug/kg/5D-I
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of endocrine pancreas Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion) Related to Chronic Data - death
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,3467,1974