Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Lixazinone
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94192-59-3

94192-59-3 structure

Name: Lixazinone
Chemical Name: N-cyclohexyl-N-methyl-4-[(2-oxo-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-7-yl)oxy]butanamide
CAS Number: 94192-59-3
Molecular Formula: C₂₁H₂₈N₄O₃
Molecular Weight: 384.47200
Create Date: 2018-03-30 08:00:00
Modify Date: 2024-01-10 17:15:11

Name	N-cyclohexyl-N-methyl-4-[(2-oxo-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-7-yl)oxy]butanamide
Synonyms	Lixazinonum [Latin] Butanamide,N-cyclohexyl-N-methyl-4-((1,2,3,5-tetrahydro-2-oxoimidazo(2,1-b)quinazolin-7-yl)oxy) Lixazinonum Butanamide,N-cyclohexyl-N-methyl-4-((2-oxo-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-7-yl)oxy) Lixazinone N-cyclohexyl-N-methyl-4-(2-oxo-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-7-yl)oxybutyramide Lixazinona Lixazinona [Spanish] Lixazinone [INN]

Density	1.33g/cm3
Boiling Point	579.2ºC at 760 mmHg
Molecular Formula	C₂₁H₂₈N₄O₃
Molecular Weight	384.47200
Flash Point	304.1ºC
Exact Mass	384.21600
PSA	74.24000
LogP	2.27190
Index of Refraction	1.659

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ3510100

CHEMICAL NAME :: Butanamide, N-cyclohexyl-N-methyl-4-((2-oxo-1,2,3,5-tetrahydroimi dazo(2,1-b)quinazolin -7-yl) oxy)-

CAS REGISTRY NUMBER :: 94192-59-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4663320

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4663320

94193-38-1

94192-59-3

Literature: Venuti, Michael C.; Alvarez, Robert; Bruno, John J.; Strosberg, Arthur M.; Gu, Leo; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2145 - 2152

100-60-7

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

42454-06-8

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

94193-35-8

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

105763-67-5

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

94193-36-9

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

94193-37-0

94192-59-3

Literature: Jones; Venuti; Alvarez; Bruno; Berks; Prince Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 295 - 303

114703-82-1

94192-59-3

Literature: Venuti, Michael C.; Alvarez, Robert; Bruno, John J.; Strosberg, Arthur M.; Gu, Leo; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2145 - 2152

Precursor 4
100-60-7 42454-06-8 105763-67-5 94193-36-9
DownStream 0

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