121250-06-4

121250-06-4 structure

121250-06-4 structure

Name: 14-Chloro Daunorubicin
Chemical Name: 14-Chloro Daunorubicin
CAS Number: 121250-06-4
Molecular Formula: C₂₇H₂₈ClNO₁₀
Molecular Weight: 561.96500
Create Date: 2017-12-18 19:39:45
Modify Date: 2024-01-17 17:36:18

Name	14-Chloro Daunorubicin
Synonyms	14-chlorodaunorubicin 14-ChlororuboMycin 10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-(2-chloroacetyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione 14-ChlorodaunoMycin

Density	1.6g/cm3
Boiling Point	793.8ºC at 760mmHg
Molecular Formula	C₂₇H₂₈ClNO₁₀
Molecular Weight	561.96500
Flash Point	433.9ºC
Exact Mass	561.14000
PSA	185.84000
LogP	1.94810
Vapour Pressure	1.43E-26mmHg at 25°C
Index of Refraction	1.695

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI9325500

CHEMICAL NAME :: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha -L-lyxo- hexopyranosyl)oxy)-8-(chloroacetyl)-1-methoxy-6,8,11- trihydroxy-, (8S-cis)-

CAS REGISTRY NUMBER :: 121250-06-4

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H28-Cl-N-O10

MOLECULAR WEIGHT :: 562.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 33500 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: ANKHEW Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. (V/O Me zhdunarodnaya Kniga, 113095 Moskow, USSR) V.33- 1988- Volume(issue)/page/year: 35(2),24,1990