185835-97-6

185835-97-6 structure

Name: (5S)-5-(METHOXYMETHYL)-3-[6-(4,4,4-TRIFLUOROBUTOXY)-1,2-BENZOXAZOL-3-YL]-1,3-OXAZOLIDIN-2-ONE
Chemical Name: sl-25.1188
CAS Number: 185835-97-6
Molecular Formula: C₁₆H₁₇F₃N₂O₅
Molecular Weight: 374.31
Create Date: 2017-08-08 22:33:48
Modify Date: 2024-02-17 19:28:56
SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].

Name	sl-25.1188
Synonyms	(5S)-5-(methoxymethyl)-3-[6-(4,4,4-trifluorobutoxy)-1,2-benzoxazol-3-yl]-1,3-oxazolidin-2-one 2-Oxazolidinone,5-(methoxymethyl)-3-[6-(4,4,4-trifluorobutoxy)-1,2-benzisoxazol-3-yl]-,(5S) 2-Oxazolidinone,5-(methoxymethyl)-3-[6-(4,4,4-trifluorobutoxy)-1,2-benzisoxazol-3-yl]-,(S)

Description	SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Target	hMAO-B:2.9 nM (Ki) rMAO-B:8.5 nM (Ki)
References	[1]. Saba W, et, al. [(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64(1):61-9.