71598-10-2

71598-10-2 structure

71598-10-2 structure

Name: 1-nitro-2-nitroso-1-propylguanidine
Chemical Name: 1-nitro-2-nitroso-1-propylguanidine
CAS Number: 71598-10-2
Molecular Formula: C₄H₉N₅O₃
Molecular Weight: 175.14600
Create Date: 2017-05-09 07:20:15
Modify Date: 2024-04-05 18:02:38

Name	1-nitro-2-nitroso-1-propylguanidine
Synonyms	PNNG GUANIDINE,1-NITRO-3-NITROSO-1-PROPYL 3-Nitroso-1-nitro-1-propylguanidine

Density	1.514g/cm3
Boiling Point	295.815ºC at 760 mmHg
Molecular Formula	C₄H₉N₅O₃
Molecular Weight	175.14600
Flash Point	132.704ºC
Exact Mass	175.07100
PSA	117.86000
LogP	1.28920
Index of Refraction	1.594

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF4640000

CHEMICAL NAME :: Guanidine, 1-nitro-3-nitroso-1-propyl-

CAS REGISTRY NUMBER :: 71598-10-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C4-H9-N5-O3

MOLECULAR WEIGHT :: 175.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2172 mg/kg/52W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 mg/kg/5W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2172 mg/kg/52W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3080 mg/kg/44W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3665 mg/kg/44W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Unscheduled DNA synthesis

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 10 mg/L

REFERENCE :: GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981