1094614-85-3
1094614-85-3 structure
- Name: BIX02189
- Chemical Name: bix 02189
- CAS Number: 1094614-85-3
- Molecular Formula: C27H28N4O2
- Molecular Weight: 440.54
- Catalog: Biochemical Inhibitor Mitogen-activated protein kinase (MAPK) MEK inhibitor
- Create Date: 2018-12-16 20:18:32
- Modify Date: 2024-01-15 19:44:50
-
(E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
| Name | bix 02189 |
|---|---|
| Synonyms |
1H-Indole-6-carboxamide, 3-[[[3-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N,N-dimethyl-2-oxo-, (3Z)-
(3Z)-3-[({3-[(Dimethylamino)methyl]phenyl}amino)(phenyl)methylene]-N,N-dimethyl-2-oxo-6-indolinecarboxamide BIX02189 |
| Description | (E/Z)-BIX02189 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | |
| In Vitro | BIX 02189 是一种选择性的 MEK5 抑制剂，IC50 为 1.5 nM，也抑制 ERK5 的催化活性，IC50 为 810 nM，而不抑制其密切相关的激酶 MEK1、MEK2、ERK2 和 JNK2。 |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 653.4±55.0 °C at 760 mmHg |
| Molecular Formula | C27H28N4O2 |
| Molecular Weight | 440.54 |
| Flash Point | 349.0±31.5 °C |
| Exact Mass | 440.221222 |
| PSA | 64.68000 |
| LogP | 2.05 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.659 |
| Storage condition | -20℃ |