Name | 6-phenylpyridine-3-carboxylic acid |
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Synonyms |
3-Pyridinecarboxylic acid, 6-phenyl-
6-phenylpyridine-3-carboxylic acid 6-Phenyl-nicotinic acid 3-Carboxy-6-phenylpyridine 6-phenyl-3-pyridinecarboxylic acid 6-Phenylnicotinic acid 2-phenyl-5-carboxypyridine 6-Phenyl-nicotinsaeure 2-phenyl-5-pyridinecarboxylic acid |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 388.1±30.0 °C at 760 mmHg |
Melting Point | 243ºC |
Molecular Formula | C12H9NO2 |
Molecular Weight | 199.205 |
Flash Point | 188.5±24.6 °C |
Exact Mass | 199.063324 |
PSA | 50.19000 |
LogP | 2.15 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.613 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 29051-44-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: odorless - slight odor pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 232 - 233 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H9NO2 Molecular Weight: 199.21 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Reducing agents, strong oxidizing agents, bases, amines. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 29051-44-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 6-Phenylnicotinic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 29051-44-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 29051-44-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 29051-44-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
HS Code | 2933399090 |
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~87% 29051-44-3 |
Literature: Steunenberg, Peter; Ruggi, Albert; Van Den Berg, Nynke S.; Buckle, Tessa; Kuil, Joeri; Van Leeuwen, Fijs W.B.; Velders, Aldrik H. Inorganic Chemistry, 2012 , vol. 51, # 4 p. 2105 - 2114 |
~% 29051-44-3 |
Literature: Merck and Co., Inc. Patent: US5872136 A1, 1999 ; |
~49% 29051-44-3 |
Literature: Coteron, Jose M.; Catterick, David; Castro, Julia; Chaparro, Maria J.; Diaz, Beatriz; Fernandez, Esther; Ferrer, Santiago; Gamo, Francisco J.; Gordo, Mariola; Gut, Jiri; De Las Heras, Laura; Legac, Jennifer; Marco, Maria; Miguel, Juan; Munoz, Vicente; Porras, Esther; De La Rosa, Juan C.; Ruiz, Jose R.; Sandoval, Elena; Ventosa, Pilar; Rosenthal, Philip J.; Fiandor, Jose M. Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6129 - 6152 |
~% 29051-44-3 |
Literature: Yu, Ming; Lizarzaburu, Mike; Beckmann, Holger; Connors, Richard; Dai, Kang; Haller, Katrin; Li, Cong; Liang, Lingming; Lindstrom, Michelle; Ma, Ji; Motani, Alykhan; Wanska, Malgorzata; Zhang, Alex; Li, Leping; Medina, Julio C. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1758 - 1762 |
~% 29051-44-3 |
Literature: Abramovitch et al. Tetrahedron Letters, 1959 , # 8 p. 1 Canadian Journal of Chemistry, 1960 , vol. 38, p. 761,770 |
~% 29051-44-3 |
Literature: CIBA Patent: CH192504 , 1934 ; |
~% 29051-44-3 |
Literature: Benary; Psille Chemische Berichte, 1924 , vol. 57, p. 833 |
Precursor 7 | |
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DownStream 3 | |
HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |