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29051-44-3

29051-44-3 structure
29051-44-3 structure

Name 6-phenylpyridine-3-carboxylic acid
Synonyms 3-Pyridinecarboxylic acid, 6-phenyl-
6-phenylpyridine-3-carboxylic acid
6-Phenyl-nicotinic acid
3-Carboxy-6-phenylpyridine
6-phenyl-3-pyridinecarboxylic acid
6-Phenylnicotinic acid
2-phenyl-5-carboxypyridine
6-Phenyl-nicotinsaeure
2-phenyl-5-pyridinecarboxylic acid
Density 1.2±0.1 g/cm3
Boiling Point 388.1±30.0 °C at 760 mmHg
Melting Point 243ºC
Molecular Formula C12H9NO2
Molecular Weight 199.205
Flash Point 188.5±24.6 °C
Exact Mass 199.063324
PSA 50.19000
LogP 2.15
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.613
Name: 6-Phenylnicotinic acid 90+% Material Safety Data Sheet
Synonym:
CAS: 29051-44-3
Section 1 - Chemical Product MSDS Name:6-Phenylnicotinic acid 90+% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
29051-44-3 6-Phenylnicotinic acid 90+% 249-386-4
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 29051-44-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: odorless - slight odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 232 - 233 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H9NO2
Molecular Weight: 199.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Reducing agents, strong oxidizing agents, bases, amines.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 29051-44-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
6-Phenylnicotinic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 29051-44-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 29051-44-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 29051-44-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
HS Code 2933399090

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29051-44-3 structure

29051-44-3

Literature: Steunenberg, Peter; Ruggi, Albert; Van Den Berg, Nynke S.; Buckle, Tessa; Kuil, Joeri; Van Leeuwen, Fijs W.B.; Velders, Aldrik H. Inorganic Chemistry, 2012 , vol. 51, # 4 p. 2105 - 2114

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29051-44-3 structure

29051-44-3

Literature: Merck and Co., Inc. Patent: US5872136 A1, 1999 ;

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29051-44-3 structure

29051-44-3

Literature: Coteron, Jose M.; Catterick, David; Castro, Julia; Chaparro, Maria J.; Diaz, Beatriz; Fernandez, Esther; Ferrer, Santiago; Gamo, Francisco J.; Gordo, Mariola; Gut, Jiri; De Las Heras, Laura; Legac, Jennifer; Marco, Maria; Miguel, Juan; Munoz, Vicente; Porras, Esther; De La Rosa, Juan C.; Ruiz, Jose R.; Sandoval, Elena; Ventosa, Pilar; Rosenthal, Philip J.; Fiandor, Jose M. Journal of Medicinal Chemistry, 2010 , vol. 53, # 16 p. 6129 - 6152

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29051-44-3 structure

29051-44-3

Literature: Yu, Ming; Lizarzaburu, Mike; Beckmann, Holger; Connors, Richard; Dai, Kang; Haller, Katrin; Li, Cong; Liang, Lingming; Lindstrom, Michelle; Ma, Ji; Motani, Alykhan; Wanska, Malgorzata; Zhang, Alex; Li, Leping; Medina, Julio C. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1758 - 1762

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29051-44-3 structure

29051-44-3

Literature: Abramovitch et al. Tetrahedron Letters, 1959 , # 8 p. 1 Canadian Journal of Chemistry, 1960 , vol. 38, p. 761,770

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29051-44-3 structure

29051-44-3

Literature: CIBA Patent: CH192504 , 1934 ;

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29051-44-3 structure

29051-44-3

Literature: Benary; Psille Chemische Berichte, 1924 , vol. 57, p. 833
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%