54897-62-0

54897-62-0 structure
54897-62-0 structure
  • Name: N-ETHYL-N-BUTAN-4-OL-NITROSAMINE
  • Chemical Name: N-ethyl-N-(4-hydroxybutyl)nitrous amide
  • CAS Number: 54897-62-0
  • Molecular Formula: C6H14N2O2
  • Molecular Weight: 146.18800
  • Create Date: 2019-04-29 11:19:51
  • Modify Date: 2024-01-06 16:40:49

Name N-ethyl-N-(4-hydroxybutyl)nitrous amide
Synonyms EHBN
N-Ethyl-n-butan-4-ol-nitrosamine
N-Ethyl-N-nitroso-4-aminobutanol
Density 1.05
Boiling Point 140ºC / 4mmHg
Molecular Formula C6H14N2O2
Molecular Weight 146.18800
Flash Point 131.4ºC
Exact Mass 146.10600
PSA 52.90000
LogP 0.76220
Index of Refraction 1.472

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL3870000
CHEMICAL NAME :
1-Butanol, 4-(ethylnitrosoamino)-
CAS REGISTRY NUMBER :
54897-62-0
LAST UPDATED :
199612
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C6-H14-N2-O2
MOLECULAR WEIGHT :
146.22
WISWESSER LINE NOTATION :
Q4N2&NO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4375 mg/kg/20W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4900 mg/kg/14W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
24 gm/kg/20W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
59 gm/kg/20W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5300 mg/kg/20W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9800 mg/kg/14W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7 gm/kg/120W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7000 mg/kg/20W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4704 mg/kg/20W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
35 umol/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,399,1977
RTECS EL3870000

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54897-62-0 structure

54897-62-0

Literature: Chemical and Pharmaceutical Bulletin, , vol. 26, # 12 p. 3891 - 3896
Precursor  1

DownStream  1