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  • DC Chemicals Limited
  • China
  • Product Name: PP30
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1092788-09-4

1092788-09-4 structure
1092788-09-4 structure

Name 3-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4,5-d ihydro-1,3-thiazol-2-yl)benzamide
Description PP30, a TORKinib, is a potent, selective, and ATP-competitive inhibitor of mTOR with an IC50 of 80 nM.
Related Catalog
Target

p110δ:0.99 μM (IC50)

p110γ:0.68 μM (IC50)

References

[1]. Morris E Feldman, et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10;7(2):e38.

Molecular Formula C18H19N7OS
Molecular Weight 381.45500
Exact Mass 381.13700
PSA 139.87000
LogP 3.08060