75220-84-7
75220-84-7 structure
- Name: Anticonvulsant agent 2
- Chemical Name: 4-(4-chlorophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine
- CAS Number: 75220-84-7
- Molecular Formula: C21H17ClN2
- Molecular Weight: 332.83
- Catalog: Research Areas Neurological Disease
- Create Date: 2017-03-13 00:37:36
- Modify Date: 2024-01-29 16:49:18
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Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1].
| Name | 4-(4-chlorophenyl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine |
|---|
| Description | Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1]. |
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| Related Catalog | |
| In Vivo | Anticonvulsant agent 2 (compound10 a; 50 mg/kg, p.o.) 降低大鼠运动活性，抑制率为 21.01%[1]。 Anticonvulsant agent 2 (50 mg/kg; p.o.) 显示出抗癫痫活性，对大鼠的抑制率为24.45%[1]。 Animal Model: 180-250g, male Wistar rats[1] Dosage: 50 mg/kg Administration: P.o. Result: Showed antiepileptic activity with the inhibition rate of 24.45%. |
| References |
| Molecular Formula | C21H17ClN2 |
|---|---|
| Molecular Weight | 332.83 |
| Exact Mass | 332.10800 |
| PSA | 24.39000 |
| LogP | 5.59130 |
|
~90%
75220-84-7 |
| Literature: Du, Yuying; Tian, Fuli Journal of Chemical Research, 2006 , # 8 p. 486 - 489 |
|
~59%
75220-84-7 |
| Literature: Orlov, V. D.; Kolos, N. N.; Yaremenko, F. G.; Lavrushin, V. F. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 5 p. 547 - 550 Khimiya Geterotsiklicheskikh Soedinenii, 1980 , # 5 p. 697 - 700 |
|
~%
75220-84-7 |
| Literature: Verma, Anil K.; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K. Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1064 - 1073 |
|
~%
75220-84-7 |
| Literature: Verma, Anil K.; Koul, Summon; Razdan, Tej K.; Kapoor, Kamal K. Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1064 - 1073 |
![2-Phenyl-1H-benzo[d]imidazole structure](https://image.chemsrc.com/caspic/350/716-79-0.png)