137215-12-4

137215-12-4 structure

Name: Odiparcil
Chemical Name: 4-methyl-7-[(5-thio-beta-D-xylopyranosyl)oxy]-2H-1-benzopyran-2-one
CAS Number: 137215-12-4
Molecular Formula: C₁₅H₁₆O₆S
Molecular Weight: 324.34900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Thrombin
Create Date: 2017-09-08 04:24:14
Modify Date: 2024-01-01 18:11:41
Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2].

Name	4-methyl-7-[(5-thio-beta-D-xylopyranosyl)oxy]-2H-1-benzopyran-2-one

Description	Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin
Target	Thrombin[2]
References	[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70 [2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.