347840-03-3

347840-03-3 structure
347840-03-3 structure
  • Name: N,N-Dimethylglycine-d6 hydrochloride
  • Chemical Name: 2-[bis(trideuteriomethyl)amino]acetic acid,hydrochloride
  • CAS Number: 347840-03-3
  • Molecular Formula: C4H4D6ClNO2
  • Molecular Weight: 145.62
  • Create Date: 2018-12-25 17:11:01
  • Modify Date: 2024-01-23 20:27:37
  • N,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].

Name 2-[bis(trideuteriomethyl)amino]acetic acid,hydrochloride
Synonyms N,N-Dimethyl-d6-glycine hydrochloride
N-Methylsarcosine-dimethyl-d6 hydrochloride
Description N,N-Dimethylglycine-d6 hydrochloride is the deuterium labeled N,N-Dimethylglycine[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Boiling Point 190-192ºC(lit.)
Molecular Formula C4H4D6ClNO2
Molecular Weight 145.62
Exact Mass 145.07800
PSA 40.54000
LogP 0.43460
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/38
Safety Phrases 26-36/37
RIDADR NONH for all modes of transport