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34675-77-9

34675-77-9 structure
34675-77-9 structure
  • Name: Centpropazine
  • Chemical Name: 1-[4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]phenyl]propan-1-one
  • CAS Number: 34675-77-9
  • Molecular Formula: C22H28N2O3
  • Molecular Weight: 368.46900
  • Create Date: 2018-12-01 19:43:26
  • Modify Date: 2024-01-12 10:08:46

Name 1-[4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]phenyl]propan-1-one
Synonyms Centpropazine
Centropazine
Density 1.147g/cm3
Boiling Point 560.7ºC at 760mmHg
Molecular Formula C22H28N2O3
Molecular Weight 368.46900
Flash Point 292.9ºC
Exact Mass 368.21000
PSA 53.01000
LogP 2.84410
Index of Refraction 1.576

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UC2984000
CHEMICAL NAME :
1-Propanone, 1-(4-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phe nyl)-
CAS REGISTRY NUMBER :
34675-77-9
BEILSTEIN REFERENCE NO. :
0578135
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H28-N2-O3
MOLECULAR WEIGHT :
368.52
WISWESSER LINE NOTATION :
T6N DNTJ A1YQ1OR DV2& DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
1710 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,338,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Behavioral - wakefulness
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,286,1972
HS Code 2933599090
HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%