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630125-49-4

630125-49-4 structure
630125-49-4 structure

Name 3-Bromo-5-nitrobenzotrifluoride
Synonyms 1-Bromo-3-nitro-5-(trifluoromethyl)benzene
Benzene, 1-bromo-3-nitro-5-(trifluoromethyl)-
MFCD03788719
3-bromo-5-nitrobenzotrifluoride
Density 1.8±0.1 g/cm3
Boiling Point 223.7±35.0 °C at 760 mmHg
Molecular Formula C7H3BrF3NO2
Molecular Weight 270.003
Flash Point 89.1±25.9 °C
Exact Mass 268.929932
PSA 45.82000
LogP 2.89
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.514
Storage condition Room temperature.
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1-Bromo-3-nitro-5-trifluoromethylbenzene
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H312:Harmful in contact with skin
H332:Harmful if inhaled
H315:Causes skin irritation
H319:Causes serious eye irritation
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P337+P313:If eye irritation persists get medical advice/attention

Section3. Composition/information on ingredients.
Ingredient name:1-Bromo-3-nitro-5-trifluoromethylbenzene
CAS number:630125-49-4

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not specified
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C7H3BrF3NO2
Molecular weight:270.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride, hydrogen bromide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi
Risk Phrases R20/21/22
Safety Phrases S26-S36/37/39
HS Code 2904909090

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630125-49-4 structure

630125-49-4

Literature: NOVARTIS AG; NOVARTIS PHARMA GmbH Patent: WO2006/135640 A2, 2006 ; Location in patent: Page/Page column 25-26 ;
Precursor  1

DownStream  1

HS Code 2904909090
Summary HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%