Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-(1-(2-(1H-INDOL-3-YL)ETHYL)PIPERIDIN-4-YL)BENZAMIDE HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

38821-52-2

38821-52-2 structure

Name: N-(1-(2-(1H-INDOL-3-YL)ETHYL)PIPERIDIN-4-YL)BENZAMIDE HYDROCHLORIDE
Chemical Name: N-[1-[2-(1H-Indol-3-yl)ethyl]-4-piperidinyl] benzamide hydrochloride
CAS Number: 38821-52-2
Molecular Formula: C₂₂H₂₆ClN₃O
Molecular Weight: 383.91
Catalog: Research Areas Others
Create Date: 2018-02-10 08:00:00
Modify Date: 2024-01-06 09:45:27
Indoramin (hydrochloride) is a new hypotensive agent.? Indoramin (hydrochloride) is also selective for the α1A-adrenoceptor[1].

Name	N-[1-[2-(1H-Indol-3-yl)ethyl]-4-piperidinyl] benzamide hydrochloride
Synonyms	N-[1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl]benzamide,hydrochloride Indoramin hydrochloride Benzamide, N-[1-[2-(1H-indol-3-yl)ethyl]-4-piperidinyl]-, hydrochloride (1:1) N-{1-[2-(1H-Indol-3-yl)ethyl]-4-piperidinyl}benzamide hydrochloride (1:1) N-{1-[2-(1H-Indol-3-yl)ethyl]piperidin-4-yl}benzamide hydrochloride (1:1)

Description	Indoramin (hydrochloride) is a new hypotensive agent.? Indoramin (hydrochloride) is also selective for the α1A-adrenoceptor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. R B Royds, et al. The effect of indoramin on peripheral blood flow. Br J Clin Pharmacol. 1974, 13, 7.

Boiling Point	600ºC at 760mmHg
Molecular Formula	C₂₂H₂₆ClN₃O
Molecular Weight	383.91
Flash Point	316.7ºC
Exact Mass	383.176453
PSA	51.62000
LogP	4.91950

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5396000

CHEMICAL NAME :: Benzamide, N-(1-(2-(1H-indol-3-yl)ethyl)-4-piperidinyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 38821-52-2

LAST UPDATED :: 199707

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C22-H25-N3-O.Cl-H

MOLECULAR WEIGHT :: 383.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 7 mg/kg/1W-I

TOXIC EFFECTS :: Behavioral - wakefulness Behavioral - excitement Cardiac - pulse rate increase, without fall in BP

REFERENCE :: PRACAK Practitioner. (Morgan-Grampian Ltd., 40 Beresford St., Woolwich, London SE18 6BQ, UK) V.1- 1868- Volume(issue)/page/year: 228,362,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 43NDAD "Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980 Volume(issue)/page/year: -,161,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 43NDAD "Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980 Volume(issue)/page/year: -,161,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 43NDAD "Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980 Volume(issue)/page/year: -,161,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 43NDAD "Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980 Volume(issue)/page/year: -,161,1980

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
RTECS	CV5396000
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1158522-08-7	940364-43-2
134104-43-1	131615-57-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4
849349-65-1	127437-46-1