CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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LY5200000
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CHEMICAL NAME :
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Germanium, metal powder
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CAS REGISTRY NUMBER :
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7440-56-4
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LAST UPDATED :
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199701
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DATA ITEMS CITED :
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9
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MOLECULAR FORMULA :
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Ge
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MOLECULAR WEIGHT :
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72.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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58 mg/kg/26W-I
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TOXIC EFFECTS :
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Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
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REFERENCE :
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JJMDAT Japanese Journal of Medicine. (Nankodo Co., Ltd., POB 5272, Tokyo International 100-31, Japan) V.1-30, 1962-1991. For publisher information, see IEDIEP. Volume(issue)/page/year: 30,67,1991
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - child
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DOSE/DURATION :
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2 gm/kg/78W-I
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TOXIC EFFECTS :
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Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - changes in both tubules and glomeruli
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REFERENCE :
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JJMDAT Japanese Journal of Medicine. (Nankodo Co., Ltd., POB 5272, Tokyo International 100-31, Japan) V.1-30, 1962-1991. For publisher information, see IEDIEP. Volume(issue)/page/year: 30,67,1991
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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786 mg/kg/2Y-I
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TOXIC EFFECTS :
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Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - oxidant related (GPD deficient) anemia
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REFERENCE :
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JJMDAT Japanese Journal of Medicine. (Nankodo Co., Ltd., POB 5272, Tokyo International 100-31, Japan) V.1-30, 1962-1991. For publisher information, see IEDIEP. Volume(issue)/page/year: 30,67,1991
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TYPE OF TEST :
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LCLo - Lowest published lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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3860 mg/m3/4H
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 28,571,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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250 mg/m3/6H/4W-I
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - changes in lung weight Kidney, Ureter, Bladder - urine volume increased Blood - other changes
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REFERENCE :
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FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 28,571,1990 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 34770 No. of Facilities: 56 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 307 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 34770 No. of Facilities: 16 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 1914 (estimated) No. of Female Employees: 279 (estimated)
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