22467-07-8

22467-07-8 structure

22467-07-8 structure

Name: Gymnemagenin
Chemical Name: protoaescigenin
CAS Number: 22467-07-8
Molecular Formula: C₃₀H₅₀O₆
Molecular Weight: 506.714
Catalog: analytical chemistry Standard Analytical standard
Create Date: 2018-07-31 09:20:59
Modify Date: 2024-01-04 16:24:18
Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2].

Name	protoaescigenin
Synonyms	Protoaescigenin Olean-12-ene-3,16,21,22,23,28-hexol, (3β,16β,21β,22α)- (3β,16β,21β,22α)-Olean-12-ene-3,16,21,22,23,28-hexol Gymnemagenin

Description	Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats[2]. Gymnemagenin has a short half-life and a high clearance in rats[2]. Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2].
References	[1]. Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52. [2]. In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study.

Density	1.2±0.1 g/cm3
Boiling Point	634.5±55.0 °C at 760 mmHg
Melting Point	330-331℃
Molecular Formula	C₃₀H₅₀O₆
Molecular Weight	506.714
Flash Point	262.0±26.1 °C
Exact Mass	506.360748
PSA	121.38000
LogP	3.98
Vapour Pressure	0.0±4.2 mmHg at 25°C
Index of Refraction	1.598

RIDADR	NONH for all modes of transport