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  • DC Chemicals Limited
  • China
  • Product Name: AZD3264
  • Price: $680.0/100mg $1224.0/250mg $2448.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1609281-86-8

1609281-86-8 structure
1609281-86-8 structure
  • Name: AZD3264
  • Chemical Name: azd3264
  • CAS Number: 1609281-86-8
  • Molecular Formula: C21H23N5O4S
  • Molecular Weight: 441.503
  • Catalog: Signaling Pathways NF-κB IKK
  • Create Date: 2017-01-08 22:18:06
  • Modify Date: 2024-01-09 22:22:55
  • AZD3264 is a selective IkB-kinase IKK2 inhibitor.

Name azd3264
Synonyms 2-(Carbamoylamino)-5-{4-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3S)-3-pyrrolidinyloxy]phenyl}-3-thiophenecarboxamide
3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-[4-(3,5-dimethyl-4-isoxazolyl)-2-[(3S)-3-pyrrolidinyloxy]phenyl]-
Description AZD3264 is a selective IkB-kinase IKK2 inhibitor.
Related Catalog
Target

IKK2

In Vivo AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma[1].
References

[1]. Andiappan Murugan, et al. Exploiting the Differential Reactivities of Halogen Atoms: Development of a Scalable Route to IKK2 Inhibitor AZD3264. Org Process Res Dev. 2014 Apr 29;18(5): 646-651.

Density 1.4±0.1 g/cm3
Boiling Point 614.2±55.0 °C at 760 mmHg
Molecular Formula C21H23N5O4S
Molecular Weight 441.503
Flash Point 325.2±31.5 °C
Exact Mass 441.147064
LogP 2.08
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.653
Storage condition -20℃