1086136-22-2

1086136-22-2 structure

Name: L-Pyroglutamic acid-d5
Chemical Name: d5-(S)-pyroglutamic acid
CAS Number: 1086136-22-2
Molecular Formula: C₅H₂D₅NO₃
Molecular Weight: 134.14
Create Date: 2018-05-10 17:17:38
Modify Date: 2024-01-02 15:36:45
L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

Name	d5-(S)-pyroglutamic acid

Description	L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.