117442-29-2

117442-29-2 structure

Name: Xenopsin-Related Peptide 2 (XP-2) trifluoroacetate salt
Chemical Name: xenopsin
CAS Number: 117442-29-2
Molecular Formula: C₆₀H₈₈N₁₆O₁₀
Molecular Weight: 1193.44000
Catalog: Research Areas Metabolic Disease
Create Date: 2018-04-08 02:08:07
Modify Date: 2024-01-19 17:29:59
Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as synthetic Bradykinin (HY-P0206)[1].

Name	xenopsin
Synonyms	Xenopsin-Related Peptide 2 (XP-2)

Description	Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as synthetic Bradykinin (HY-P0206)[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Synthetic and native preparations of Xenopsin-Related Peptide 2 (XP-2) increases vascular permeability in rats and released histamine from isolated rat mast cells at submicromolar concentrations[1].
In Vivo	Xenopsin-Related Peptide 2 (XP-2) (0.3-3000 nM; intradermally; 50 μL) induces skin vascular permeability in rats[1]. Animal Model: Rats weighing 300-400 g[1] Dosage: 0.3-3000 nM Administration: Intradermal injection, 50 μL Result: Increased skin vascular permeability in a dose-dependent manner.
References	[1]. Carraway RE, et al. Xenopsin-related peptide generated in avian gastric extracts. Regul Pept. 1988 Sep;22(4):303-14.