Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: leucomycin A6
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Purity: 98.0%
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18361-48-3

18361-48-3 structure

18361-48-3 structure

Name: leucomycin A6
Chemical Name: [6-[6-[[(11Z,13E)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] propanoate
CAS Number: 18361-48-3
Molecular Formula: C₄₀H₆₅NO₁₅
Molecular Weight: 799.94200
Create Date: 2016-06-22 21:49:57
Modify Date: 2024-01-30 15:48:40

Name	[6-[6-[[(11Z,13E)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] propanoate
Synonyms	Antibiotic yl-704 B3 Turimycin A3 Platenomycin-B3 Leucomycin V 3-acetate 4b-propanoate Yl 704 B3 Leucomycin A6 Leukomycin A6

Density	1.22g/cm3
Boiling Point	867ºC at 760mmHg
Molecular Formula	C₄₀H₆₅NO₁₅
Molecular Weight	799.94200
Flash Point	478.1ºC
Exact Mass	799.43500
PSA	206.05000
LogP	2.37730
Vapour Pressure	4.52E-35mmHg at 25°C
Index of Refraction	1.537

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OH4725500

CHEMICAL NAME :: Leucomycin A6

CAS REGISTRY NUMBER :: 18361-48-3

LAST UPDATED :: 199512

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C40-H65-N-O15

MOLECULAR WEIGHT :: 800.06

WISWESSER LINE NOTATION :: T-16-OV KU MUTJ DOO2 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV2 DQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,810,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,87,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 4,193,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309