2618-41-9
2618-41-9 structure
- Name: Miroestrol
- Chemical Name: miroestrol
- CAS Number: 2618-41-9
- Molecular Formula: C20H22O6
- Molecular Weight: 358.38500
- Catalog: Research Areas Cancer
- Create Date: 2018-02-01 12:17:21
- Modify Date: 2024-01-10 15:41:58
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Miroestrol is a highly active phytoestrogen. Miroestrol can produce mammogenic effect. Miroestrol exhibits bone loss prevention and neuroprotective in ovariectomized mice. Miroestrol also can reduce cancer risk[1][2][3][4].
| Name | miroestrol |
|---|---|
| Synonyms | Miroestrol |
| Description | Miroestrol is a highly active phytoestrogen. Miroestrol can produce mammogenic effect. Miroestrol exhibits bone loss prevention and neuroprotective in ovariectomized mice. Miroestrol also can reduce cancer risk[1][2][3][4]. |
|---|---|
| Related Catalog | |
| In Vivo | Miroestrol (0.1-1 mg/kg; s.c. once daily for 60 days) exhibits bone loss prevention via increase of the ratio of osteoprotegerin to receptor activator of nuclear factor kappa B ligand (osteoformation/osteoresorption) in ovariectomized mouse liver[2]. Miroestrol (0.1-1 mg/kg; i.p. once daily for 8 weeks) dose-dependently attenuates ovariectomized-induced cognitive dysfunction in mice[3]. Miroestrol (0.5-5 mg/kg; s.c. once daily for 7 days) suppresses hepatic CYP1A1 activity and CYP1A2 activity, expression of CYP1B1 mRNA and expression of CYP1A1/2 and CYP1B1 protein in β-naphthoflavone-treated mice[4]. |
| References |
| Molecular Formula | C20H22O6 |
|---|---|
| Molecular Weight | 358.38500 |
| Exact Mass | 358.14200 |
| PSA | 107.22000 |
| LogP | 1.22390 |