923562-23-6

923562-23-6 structure

Name: STK321130
Chemical Name: stk321130
CAS Number: 923562-23-6
Molecular Formula: C₂₁H₁₆ClF₃N₄
Molecular Weight: 416.827
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
Create Date: 2018-06-08 18:34:14
Modify Date: 2024-01-10 18:55:04
FLT3-IN-2 is a FLT3 inhibitor with IC50 of ＜ 1 μM, detailed information refer to WO 2012158957 A2 and WO 2007013896.

Name	stk321130
Synonyms	5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[4-(trifluoromethyl)benzyl]-2-pyridinamine stk321130 2-Pyridinamine, 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]- FLT3-IN-2

Description	FLT3-IN-2 is a FLT3 inhibitor with IC50 of ＜ 1 μM, detailed information refer to WO 2012158957 A2 and WO 2007013896.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3 Research Areas >> Cancer
References	[1]. Zhang, Chao, et al. Kinase modulation for the treatment of leukemias. From PCT Int. Appl. (2012), WO 2012158957 A2 20121122. [2]. Zhang Chao, et al. 7-Azaindole derivatives and their preparation, pharmaceutical compositions and use for modulating c-kit and c-fms activity. From PCT Int. Appl. (2007), WO 2007013896 A2 20070201.