152051-21-3

152051-21-3 structure

Name: ELDKWA
Chemical Name: glu-Leu-Asp-Lys-Trp-Ala
CAS Number: 152051-21-3
Molecular Formula: C₃₅H₅₂N₈O₁₁
Molecular Weight: 760.83400
Catalog: Research Areas Others
Create Date: 2018-06-26 22:37:25
Modify Date: 2024-07-18 08:42:34
ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5)directed against human immunodeficiency virus type 1[1][2].

Name	glu-Leu-Asp-Lys-Trp-Ala

Description	ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5)directed against human immunodeficiency virus type 1[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. T Muster, et al. Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol. 1994 Jun;68(6):4031-4. [2]. Y Tian, et al. Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5: effects of side-chain and backbone modifications and conformational constraints. J Pept Res. 2002 Jun;59(6):264-76.