1572936-83-4

1572936-83-4 structure

Name: MONNA
Chemical Name: monna
CAS Number: 1572936-83-4
Molecular Formula: C₁₈H₁₄N₂O₅
Molecular Weight: 338.31400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Chloride Channel
Create Date: 2018-02-05 00:37:13
Modify Date: 2024-01-10 18:00:22
MONNA is a potent transmembrane protein 16A (TMEM16A,Anoctamin-1) blocker with IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions[1].

Name	monna
Synonyms	N-((4-methoxy)-2-naphthyl)-5-nitroanthranilic acid 2-(4-methoxynaphthalen-2-ylamino)-5-nitrobenzoic acid

Description	MONNA is a potent transmembrane protein 16A (TMEM16A,Anoctamin-1) blocker with IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel Research Areas >> Cardiovascular Disease
References	[1]. Oh SJ, et al. MONNA, a potent and selective blocker for transmembrane protein with unknown function 16/anoctamin-1. Mol Pharmacol. 2013 Nov;84(5):726-35.