23027-91-0

23027-91-0 structure

Name: (16S,22R)-14α,17α-Epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone
Chemical Name: physalin A
CAS Number: 23027-91-0
Molecular Formula: C₂₈H₃₀O₁₀
Molecular Weight: 526.53200
Create Date: 2018-05-10 23:47:28
Modify Date: 2024-01-05 13:01:19
Physalin A is a withanolide isolated from Physalis alkekengi var. franchetii. Physalin A induces apoptosis associated with up-regulation of caspase-3 and caspase-8 expression. Physalin A induces autophagy, found to antagonize apoptosis in HT1080 cells. Physalin A has the potential for the research of cancer disease[1].

Name	physalin A
Synonyms	Physalin A

Description	Physalin A is a withanolide isolated from Physalis alkekengi var. franchetii. Physalin A induces apoptosis associated with up-regulation of caspase-3 and caspase-8 expression. Physalin A induces autophagy, found to antagonize apoptosis in HT1080 cells. Physalin A has the potential for the research of cancer disease[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
References	[1]. He H, et al. Physalin A induces apoptotic cell death and protective autophagy in HT1080 human fibrosarcoma cells. J Nat Prod. 2013;76(5):880-888.

Hazard Codes	Xi