528-63-2

528-63-2 structure

Name: Galgravin
Chemical Name: galgravin
CAS Number: 528-63-2
Molecular Formula: C₂₂H₂₈O₅
Molecular Weight: 372.45500
Catalog: Research Areas Cancer
Create Date: 2018-04-20 08:00:00
Modify Date: 2024-01-09 11:49:17
Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].

Name	galgravin
Synonyms	Galgravin r-2,c-5-Bis(3,4-dimethoxyphenyl)-t-3,t-4-dimethyl-tetrahydrofuran 2r,5cBis-(3,4-dimethoxy-phenyl)-3t,4t-dimethyl-tetrahydro-furan (2S,3S,4R,5R)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan

Description	Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Galgravin has cytotoxic activity against human leukemia tumor cells with an IC50 of 16.5 µg/mL[2].
References	[1]. da Silva Filho AA, et al. Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. J Pharm Pharmacol. 2004 Sep;56(9):1179-84. [2]. Ponci V, et al. Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells. Molecules. 2015 Jul 15;20(7):12757-68.