151978-50-6
151978-50-6 structure
- Name: tert-Butyl pent-4-yn-1-ylcarbamate
- Chemical Name: N-Boc-4-pentyne-1-amine
- CAS Number: 151978-50-6
- Molecular Formula: C10H17NO2
- Molecular Weight: 183.24700
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-09-08 10:35:12
- Modify Date: 2024-01-11 11:15:14
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N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122)[1].
| Name | N-Boc-4-pentyne-1-amine |
|---|---|
| Synonyms | tert-butyl N-pent-4-ynylcarbamate |
| Description | N-Boc-4-pentyne-1-amine is a PROTAC linker, which refers to the alkyl chain composition. N-Boc-4-pentyne-1-amine can be used in the synthesis of the PROTAC MG-277 (HY-130122)[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| References |
| Molecular Formula | C10H17NO2 |
|---|---|
| Molecular Weight | 183.24700 |
| Exact Mass | 183.12600 |
| PSA | 41.82000 |
| LogP | 2.12890 |
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Hazard Codes | C |
| RIDADR | UN 2735PSN1 8 / PGII |
| HS Code | 2924199090 |
|
~42%
151978-50-6 |
| Literature: WO2013/96771 A1, ; Page/Page column 215 ; |
|
~85%
151978-50-6 |
| Literature: Synthesis, , # 9 art. no. Z17611SS, p. 1477 - 1483 |
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~%
151978-50-6 |
| Literature: Organic Letters, , vol. 9, # 15 p. 2887 - 2889 |
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~%
151978-50-6 |
| Literature: US2011/152321 A1, ; |
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~%
151978-50-6 |
| Literature: WO2013/96771 A1, ; |
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~%
151978-50-6 |
| Literature: WO2013/96771 A1, ; |
| Precursor 8 | |
|---|---|
| DownStream 2 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |