23983-05-3

23983-05-3 structure
23983-05-3 structure
  • Name: WT-TTR inhibitor 1
  • Chemical Name: 2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one
  • CAS Number: 23983-05-3
  • Molecular Formula: C16H9ClN2OS
  • Molecular Weight: 312.77
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-05-17 19:37:05
  • Modify Date: 2024-02-26 10:28:54
  • WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].

Name 2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Synonyms 2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Description WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].
Related Catalog
References

[1]. Avadhesha Surolia. Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates. Patent US20100190832A1.

Molecular Formula C16H9ClN2OS
Molecular Weight 312.77
Exact Mass 312.01200
PSA 62.61000
LogP 3.11030
Storage condition -20°C