WT-TTR inhibitor 1

Modify Date: 2024-02-26 10:28:54

WT-TTR inhibitor 1 Structure
WT-TTR inhibitor 1 structure
Common Name WT-TTR inhibitor 1
CAS Number 23983-05-3 Molecular Weight 312.77
Density N/A Boiling Point N/A
Molecular Formula C16H9ClN2OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of WT-TTR inhibitor 1


WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].

 Names

Name 2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Synonym More Synonyms

 WT-TTR inhibitor 1 Biological Activity

Description WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].
Related Catalog
References

[1]. Avadhesha Surolia. Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates. Patent US20100190832A1.

 Chemical & Physical Properties

Molecular Formula C16H9ClN2OS
Molecular Weight 312.77
Exact Mass 312.01200
PSA 62.61000
LogP 3.11030
Storage condition -20°C

 Synonyms

2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-benzo[4,5]imidazo[2,1-b]thiazol-3-one