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140430-53-1

140430-53-1 structure
140430-53-1 structure
  • Name: Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate salt
  • Chemical Name: 7-Methoxycoumarin-4-acetyl-Pro-Leu-Gly-Leu-β-(2,4-dinitrophenylamino)Ala-Arg amide
  • CAS Number: 140430-53-1
  • Molecular Formula: C49H68N14O15
  • Molecular Weight: 1093.15000
  • Catalog: Research Areas Others
  • Create Date: 2018-12-31 11:50:08
  • Modify Date: 2024-01-02 22:18:59
  • MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues[1][2].

Name 7-Methoxycoumarin-4-acetyl-Pro-Leu-Gly-Leu-β-(2,4-dinitrophenylamino)Ala-Arg amide
Synonyms mca-pro-leu-gly-leu-dap(dnp)-ala-arg-nh2
Description MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues[1][2].
Related Catalog
References

[1]. Oneda H, et al. Substrate-dependent activation of thermolysin by salt. Biosci Biotechnol Biochem. 2004 Aug;68(8):1811-3.

[2]. Oneda H, et al. Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (matrilysin). J Biochem. 2003 May;133(5):571-6.

Molecular Formula C49H68N14O15
Molecular Weight 1093.15000
Exact Mass 1092.50000
PSA 457.00000
LogP 5.17360
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport