1001129-81-2
1001129-81-2 structure
- Name: LKY-047
- Chemical Name: (7S)-(+)-3-(4-nitrophenyl)acrylic acid, 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester
- CAS Number: 1001129-81-2
- Molecular Formula: C23H19NO7
- Molecular Weight: 421.39900
- Create Date: 2018-02-11 01:29:14
- Modify Date: 2023-01-15 12:23:23
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LKY-047 is a decursin derivative that potently and selectively inhibits CYP2J2, competitively inhibits CYP2J2-mediated astemizole O-demethylase and terfenadine hydroxylase activity with Ki of 0.96 and 2.61 uM, respectively.
| Name | (7S)-(+)-3-(4-nitrophenyl)acrylic acid, 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester |
|---|---|
| Synonyms | 3-(4-nitro-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl ester |
| Molecular Formula | C23H19NO7 |
|---|---|
| Molecular Weight | 421.39900 |
| Exact Mass | 421.11600 |
| PSA | 111.56000 |
| LogP | 4.56310 |