1226919-57-8

1226919-57-8 structure

1226919-57-8 structure

Name: L-Tyrosine-d5
Chemical Name: L-4-Hydroxyphenyl-d4-alanine-d1
CAS Number: 1226919-57-8
Molecular Formula: C₉H₆D₅NO₃
Molecular Weight: 186.22
Create Date: 2018-01-05 17:13:36
Modify Date: 2024-02-14 13:28:44
L-Tyrosine-d5 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

Name	L-4-Hydroxyphenyl-d4-alanine-d1

Description	L-Tyrosine-d5 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Ferreira GK, et al. Effect of L-tyrosine in vitro and in vivo on energy metabolism parameters in brain and liver of young rats. Neurotox Res. 2013 May;23(4):327-35.

Molecular Formula	C₉H₆D₅NO₃
Molecular Weight	186.22