1422554-34-4

1422554-34-4 structure

Name: BET-IN-1
Chemical Name: BET-IN-1
CAS Number: 1422554-34-4
Molecular Formula: C₂₅H₃₀N₄O₄
Molecular Weight: 450.530
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2018-05-23 23:42:51
Modify Date: 2024-01-20 17:12:49
BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1, compound example 2, has a plC50 in the range 6.0 - 7.0.IC50 value: 6.0 - 7.0 (plC50)Target: bromodomain

Name	BET-IN-1
Synonyms	1H-Imidazo[4,5-c]quinoline, 7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-1-[(1R)-2-methoxy-1-methylethyl]-2-(tetrahydro-2H-pyran-4-yl)- 7-(3,5-Dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(2R)-1-methoxy-2-propanyl]-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinoline

Description	BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1, compound example 2, has a plC50 in the range 6.0 - 7.0.IC50 value: 6.0 - 7.0 (plC50)Target: bromodomain
Related Catalog	Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain Research Areas >> Inflammation/Immunology
References	[1]. Demont Emmanuel Hubert, et al. Preparation of 4-(8-methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole, its salts and isomers and their use as bromodomain inhibitors. From PCT Int. Appl. (201