- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: N-(5-Cyclopropylamino-7-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-nicotinamide
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: MSC-2032964A
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: MSC-2032964A
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
1124381-43-6
1124381-43-6 structure
- Name: MSC 2032964A
- Chemical Name: MSC2032964A
- CAS Number: 1124381-43-6
- Molecular Formula: C16H13F3N6O
- Molecular Weight: 362.309
- Create Date: 2018-07-06 02:57:21
- Modify Date: 2024-01-09 16:18:09
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MSC 2032964A is a potent and selective ASK1 inhibitor (IC50 = 93 nM). It blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes and suppresses neuroinflammation in a mouse EAE model. MSC 2032964A is orally bioavailable and brain penetrant.
| Name | MSC2032964A |
|---|---|
| Synonyms |
N-[(2Z)-5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]nicotinamide
3-Pyridinecarboxamide, N-[(2Z)-5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2(3H)-ylidene]- MSC2032964A MFCD30182335 |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 465.2±55.0 °C at 760 mmHg |
| Molecular Formula | C16H13F3N6O |
| Molecular Weight | 362.309 |
| Flash Point | 235.1±31.5 °C |
| Exact Mass | 362.110291 |
| LogP | 1.56 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.706 |