Shanghai Nianxing Industrial Co., Ltd
China
Product Name: H2L5186303
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: H2L5186303
Price: $650.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

139262-76-3

139262-76-3 structure

139262-76-3 structure

Name: H2L5186303
Chemical Name: (2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)
CAS Number: 139262-76-3
Molecular Formula: C₂₆H₂₀N₂O₈
Molecular Weight: 488.446
Create Date: 2018-06-22 04:19:55
Modify Date: 2024-01-08 06:45:11
H2L5186303 is a potent and selective LPA2 receptor (lysophosphatidic acid 2 receptor) antagonist with an IC50 of 9 nM[1].

Name	(2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)
Synonyms	2-Butenoic acid, 4,4'-[1,3-phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-, (2Z,2'Z)- (2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)

Description	H2L5186303 is a potent and selective LPA2 receptor (lysophosphatidic acid 2 receptor) antagonist with an IC50 of 9 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> LPL Receptor
Target	LPA2 Receptor:9 nM (IC50)
References	[1]. Fells JI, et al. Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem. 2009 Nov 1;17(21):7457-64.

Density	1.4±0.1 g/cm3
Boiling Point	801.0±65.0 °C at 760 mmHg
Molecular Formula	C₂₆H₂₀N₂O₈
Molecular Weight	488.446
Flash Point	438.2±34.3 °C
Exact Mass	488.121979
LogP	4.46
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.688
Storage condition	2-8°C

RIDADR	NONH for all modes of transport