1190007-20-5

1190007-20-5 structure
1190007-20-5 structure
  • Name: Thiabendazole-d4
  • Chemical Name: 2-(1,3-Thiazol-4-yl)(4,5,6,7-2H4)-1H-benzimidazole
  • CAS Number: 1190007-20-5
  • Molecular Formula: C10H3D4N3S
  • Molecular Weight: 205.272
  • Catalog: Research Areas Others
  • Create Date: 2018-06-16 11:51:22
  • Modify Date: 2024-01-08 19:00:48
  • Thiabendazole-d4 is the deuterium labeled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephaliti

Name 2-(1,3-Thiazol-4-yl)(4,5,6,7-2H4)-1H-benzimidazole
Synonyms 2-(1,3-Thiazol-4-yl)(4,5,6,7-2H4)-1H-benzimidazole
1H-Benzimidazole-4,5,6,7-d4, 2-(4-thiazolyl)-
Description Thiabendazole-d4 is the deuterium labeled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephaliti
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Density 1.4±0.1 g/cm3
Boiling Point 446.0±37.0 °C at 760 mmHg
Molecular Formula C10H3D4N3S
Molecular Weight 205.272
Flash Point 226.2±16.9 °C
Exact Mass 205.061172
LogP 2.47
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.740
Storage condition -20°C