142797-34-0

142797-34-0 structure

Name: Silybin B
Chemical Name: Silibinin
CAS Number: 142797-34-0
Molecular Formula: C₂₅H₂₂O₁₀
Molecular Weight: 482.436
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2018-06-02 23:58:00
Modify Date: 2024-01-05 14:15:34
Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease drug candidate[1][2].

Name	Silibinin
Synonyms	MFCD03225424 SILIBININ A (2R,3R)-3,5,7-Trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one EINECS 245-302-5 [2R-[2a,3b,6(2R,3R)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one Silibinin Silybin Silybum Substance E6 33X338MNE4 MFCD00872186 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)- Dura-Silymarin

Description	Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease drug candidate[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Neurological Disease
References	[1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738. [2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

RIDADR	NONH for all modes of transport