501081-76-1

501081-76-1 structure

Name: Rilonacept
Chemical Name: Rilonacept
CAS Number: 501081-76-1
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2019-01-19 17:57:28
Modify Date: 2024-01-01 18:11:15
Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes[1].

Name	Rilonacept

Description	Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	IL-1
In Vitro	Rilonacept 通过充当结合 IL-1β 并阻止其与细胞表面受体相互作用的可溶性诱饵受体来阻断 IL-1α 信号传导，从而减少炎症过程[1]。
References	[1]. Kapur S, et, al. Rilonacept (arcalyst), an interleukin-1 trap for the treatment of cryopyrin-associated periodic syndromes. P T. 2009 Mar;34(3):138-41.

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