786686-82-6

786686-82-6 structure
786686-82-6 structure
  • Name: N-Desmethyl Olanzapine-d8
  • Chemical Name: N-DEMETHYLOLANZAPINE-D8
  • CAS Number: 786686-82-6
  • Molecular Formula: C16H10D8N4S
  • Molecular Weight: 306.46
  • Create Date: 2018-06-28 08:51:32
  • Modify Date: 2024-01-11 18:18:05
  • N-Desmethyl Olanzapine-d8 is deuterium labeled 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine.

Name N-DEMETHYLOLANZAPINE-D8
Description N-Desmethyl Olanzapine-d8 is deuterium labeled 2-Methyl-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Melting Point 129-131°C (dec.)
Molecular Formula C16H10D8N4S
Molecular Weight 306.46
Storage condition -20°C Freezer