950685-51-5

950685-51-5 structure

Name: 6-O-Methacrylate
Chemical Name: 6-O-Methacryloyltrilobolide
CAS Number: 950685-51-5
Molecular Formula: C₂₃H₃₀O₉
Molecular Weight: 450.48
Catalog: Research Areas Infection
Create Date: 2018-07-02 04:49:33
Modify Date: 2024-01-10 10:26:47
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].

Name	6-O-Methacryloyltrilobolide
Synonyms	MFCD34471092

Description	6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].
Related Catalog	Research Areas >> Infection
In Vitro	6-O-Methacrylate (10 μg/mL) shows anti-TMV activities in the pretreated tobacco plants with inhibition rate of 59.6%[2].
References	[1]. That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5. [2]. Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90.

Molecular Formula	C₂₃H₃₀O₉
Molecular Weight	450.48