177987-04-1

177987-04-1 structure

Name: 1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane
Chemical Name: Br-PEG7-Br
CAS Number: 177987-04-1
Molecular Formula: C₁₆H₃₂Br₂O₇
Molecular Weight: 496.229
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-12-02 13:23:11
Modify Date: 2024-01-04 23:19:21
Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Br-PEG7-Br
Synonyms	3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-dibromo- 1,23-Dibromo-3,6,9,12,15,18,21-heptaoxatricosane

Description	Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.