615258-40-7

615258-40-7 structure

Name: Denosumab
Chemical Name: Denosumab (usan)
CAS Number: 615258-40-7
Molecular Formula: C₆₄₀₄H₉₉₁₂N₁₇₂₄O₂₀₀₄S₅₀
Molecular Weight:
Catalog: API Antineoplastic agents Other antineoplastic agents
Create Date: 2018-12-01 08:32:33
Modify Date: 2024-01-22 02:25:33
Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].

Name	Denosumab (usan)

Description	Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].
Related Catalog	Research Areas >> Cancer
References	[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82. [2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.

Molecular Formula	C₆₄₀₄H₉₉₁₂N₁₇₂₄O₂₀₀₄S₅₀