Denosumab

Modify Date: 2024-01-22 02:25:33

Denosumab Structure
Denosumab structure
Common Name Denosumab
CAS Number 615258-40-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C6404H9912N1724O2004S50 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Denosumab


Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].

 Names

Name Denosumab (usan)

 Denosumab Biological Activity

Description Denosumab is a human monoclonal antibody binding to, and inhibiting, the receptor activator of RANKL (TNFSF11). Denosumab can reduce the risk of vertebral, nonvertebral and hip fractures[1], also has anti-cancer activity[2].
Related Catalog
References

[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82.

[2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.

 Chemical & Physical Properties

Molecular Formula C6404H9912N1724O2004S50
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