Shanghai Nianxing Industrial Co., Ltd
China
Product Name: T-26c
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: T-26c
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: T-26c
Price: $600.0/100mg $1200.0/250mg $2400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

869296-13-9

869296-13-9 structure

869296-13-9 structure

Name: T-26c
Chemical Name: T-26c
CAS Number: 869296-13-9
Molecular Formula: C₂₄H₂₁N₃O₆S
Molecular Weight: 479.51
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-06-22 06:47:10
Modify Date: 2024-01-09 16:41:38
T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].

Name	T-26c
Synonyms	CPD1612

Description	T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	IC50: 6.75 pM (MMP-13)[1]
In Vitro	T-26c significantly inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1β and oncostatin M stimulated cartilage[1].
References	[1]. Nara H, et al. Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site. Bioorg Med Chem. 2014 Oct 1;22(19):5487-505.

Molecular Formula	C₂₄H₂₁N₃O₆S
Molecular Weight	479.51