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  • DC Chemicals Limited
  • China
  • Product Name: Brd9185
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

2057420-29-6

2057420-29-6 structure
2057420-29-6 structure
  • Name: Brd9185
  • Chemical Name: BRD9185
  • CAS Number: 2057420-29-6
  • Molecular Formula: C23H21F6N3O2
  • Molecular Weight: 485.42
  • Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
  • Create Date: 2019-06-01 20:18:57
  • Modify Date: 2024-01-14 22:02:35
  • BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model[1].

Name BRD9185
Description BRD9185 is a Dihydroorotate dehydrogenase (DHODH) inhibitor, with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro and is curative after just three doses in a P. berghei mouse model[1].
Related Catalog
Target

EC50: 16 nM (DHODH in vitro)[1].

References

[1]. Maetani M, et al. Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase. ACS Med Chem Lett. 2017 Feb 27;8(4):438-442.

Molecular Formula C23H21F6N3O2
Molecular Weight 485.42