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  • DC Chemicals Limited
  • China
  • Product Name: Retro 1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

313683-81-7

313683-81-7 structure
313683-81-7 structure
  • Name: Retro 1
  • Chemical Name: 7-Bromo-5-phenyl-4-propionyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
  • CAS Number: 313683-81-7
  • Molecular Formula: C18H17BrN2O2
  • Molecular Weight: 373.244
  • Create Date: 2020-01-12 11:39:50
  • Modify Date: 2024-01-14 22:50:00
  • Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.

Name 7-Bromo-5-phenyl-4-propionyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
Synonyms 2H-1,4-Benzodiazepin-2-one, 7-bromo-1,3,4,5-tetrahydro-4-(1-oxopropyl)-5-phenyl-
MFCD00807208
7-Bromo-5-phenyl-4-propionyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
Description Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge.
References References 1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42. View Related Products by Target Other Targets
Density 1.4±0.1 g/cm3
Boiling Point 544.1±50.0 °C at 760 mmHg
Molecular Formula C18H17BrN2O2
Molecular Weight 373.244
Flash Point 282.9±30.1 °C
Exact Mass 372.047333
LogP 3.35
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.604