Name | YU142670 |
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Synonyms |
YU142670
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(4-Pyridinyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole MFCD06590438 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 3-(4-pyridinyl)- |
Description | YU142670 is a highly specific, soluble OCRL/INPP5B inhibitor that directly interacts with the catalytic domain of INPP5B; induces enhanced actin polymerization and ruffle activity at the plasma membrane, increases the levels of PI(4,5)P2 in mouse embryonic fibroblasts or human dermal fibroblasts and inhibits the activity of over-expressed human OCRL in Cos-7 cells. |
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References | References 1. Pirruccello M, et al. ACS Chem Biol. 2014 Jun 20;9(6):1359-68. View Related Products by Target Protein Phosphatase/PTP |
Density | 1.7±0.1 g/cm3 |
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Molecular Formula | C8H5N5S |
Molecular Weight | 203.224 |
Exact Mass | 203.026566 |
LogP | 1.20 |
Index of Refraction | 1.898 |